Education

  • Nov. /2019-April/2021 Advanced Postdoctoral researcher with Sophie Bombard Institute Curie, Orsay, France
  • Oct. /2016-Nov. /2019 Postdoctoral researcher with Beatrice EYMIN， COLL Jean-Luc, Gilles Subra, Florence Ruggiero Institute for Advanced Biosciences, Grenoble, France
  • Sep. /2012-Sep. /2016 PhD in Cell Biology with COLL Jean-Luc, Gilles Subra Institute for Advanced Biosciences, Grenoble, France

Awards and Scholarship

  • 2020 Springer Nature 2020 first quarter high demand (top 25%) reviewer
  • 2019-2021 Fellowship from Institute CURIE
  • 2016-2019 Fellowship from Institute National du Cancer
  • 2016-2019 Fellowship from Foundation ARC pour la Recherche on Cancer
  • 2017 Best oral presentation for young researchers in SFNano annual meeting
  • 2016 French American Doctoral Exchange Program 2016 Travel Grant
  • 2015 Prize Sanofi: Best oral presentation in European Nanomedicine Meeting
  • 2015 PhD Thesis Winner: Best oral presentation in annual meeting of Institute Albert Bonniot

Research Interest

Drug discovery, Cancer cell biology, Cell Metabolism, Vascular cell biology, DNA damage response, Signaling transduction, RNA splicing, Tumor Micro-environment and Drug Resistance, Cell adhesion and Receptor trafficking, High throughput screening, Targeted delivery, Novel Nanotechnology, near-infrared optical and confocal imaging, Data Visualization

Selected Publications and Patents

  • C.Li#, K.Kuang#, J.Du, B.Eymin, T.Jia, Far beyond Anti-angiogenesis: Benefits for anti-basicFGF Therapy in Cancer, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research (2022). https://doi.org/10.1016/j.bbamcr.2022.119253. JCR Q2
  • Manal Khalife#, Tao Jia#, Amelie Pucciarelli, Marie Leverve, Agnese Cristini, Nina Lepeltier, Cherine Abou Faycal, Carmen Garrido, Collab Oxford, Nicolas Lemaitre, Elisabeth Brambilla, Eric Solary, Olivier Sordet, Sylvie Gazzeri and Beatrice Eymin. Identification of a cross talk between splicing factor SRSF2 and DNA Damage sensor MRE11 in control of DNA damage response in lung cancer. Nature Commun. (At submission) JCR Top Journal
  • Tao Jia, Thibault Jacquet, Pauline Coudert, Elisabeth Vaganay, Chloé Exbrayat-Heritier, Maxime Henry, Veronique Josserand, Florence Ruggiero, Jean-Luc Coll and Beatrice Eymin. FGF-2 promotes angiogenesis through a SRSF1/SRSF3/SRPK1-dependent axis that controls VEGFR1 splicing in endothelial cells BMC Biology (2021) 19:173 JCR Top Journal
  • Tao Jia#; Elisabeth Vaganay#; Gilles Carpentier; Pauline Coudert; Veronica Guzman-Gonzales; Rachel Manuel; Beatrice Eymin; Jean-Luc Coll; Florence Ruggiero. A Collagen V1-derived fragment inhibits FGF-2 induced-angiogenesis by modulating endothelial cells plasticity through its heparin-binding site. Matrix Biology 2020 Dec; 94:18-30. JCR Top Journal
  • Tao Jia; Ciccione, Jeremy; Jacquet, Thibault; Maurel, Manon; Montheil, Titouan; Mehdi, Ahmad; Martinez, Jean; Eymin, Beatrice; Subra, Gilles; Coll, Jean-Luc. The presence of PEG on nanoparticles presenting the c[RGDfK]- and/or ATWLPPR peptides deeply affects the RTKs-AKT-GSK3β-eNOS signaling pathway and endothelial cells survival. International journal of pharmaceutics, 2019, 568, 118507 JCR Top Journal
  • Boudria, Asma; Abou Faycal, Cherine#; Tao Jia#; Gout, Stephanie; Keramidas, Michelle; Didier, Chloe; Lemaitre, Nicolas; Manet, Sandra; Coll, Jean-Luc; Toffart, Eymin, Beatrice. VEGF165b, a splice variant of VEGF-A, promotes lung tumor progression and escape from anti-angiogenic therapies through a β1 integrin/VEGFR autocrine loop. Oncogene, 2019 Feb;38(7):1050-1066. JCR Top Journal
  • Tao Jia; Choi, Jungyoon; Ciccione, Jeremy; Henry, Maxime; Mehdi, Ahmad; Martinez, Jean; Eymin, Beatrice; Subra, Gilles; Coll, Jean-Luc. Heteromultivalent targeting of integrin and neuropilin 1 promotes cell survival via the activation of the IGF1/insulin receptors. Biomaterials, 155(2018), 64-79 JCR Top Journal
  • Tao Jia Definition of bifunctional theranostic molecules for cancer treatment. Cellular Biology. Université Grenoble Alpes, 2016. English. ⟨NNT : 2016GREAV086⟩. ⟨tel-01686187⟩ PhD Thesis
  • Jeremie Ciccione #; Tao Jia#; Jean-Luc Coll; Karine Parra; Muriel Amblard; Said Jebors; Jean Martinez; Ahmad Mehdi; Gilles Subra. Unambiguous and controlled synthesis of multi-ligands silica nanoparticles. Chemistry of Materials, 2016, 28 (3), pp 885–889 (* Equal contribution) JCR Top Journal
  • Tao Jia; Zhang, Li; Duan, Yale; Zhang, Min; Wang, Gang; Zhang, Jun ;Zhao. The differential susceptibilities of MCF-7 and MDA-MB-231 cells to the cytotoxic effects of curcumin are associated with the PI3K/Akt-SKP2-Cip/Kips pathway. Cancer Cell Int 14, 126 (2014).
  • Tao Jia, Deepanjan Ghosh, Jean-François Betzer, Angela Marinetti, Sophie Bombard. Metallic trans-(N-Heterocyclic Carbene)-Amine-Platinum complexes and uses thereof for treating cancer. EP20306246, (2020)

Contact

  • Address: No.17, Block 3, Southern Renmin Road, Chengdu, China, 610041
  • Tel: +0086 181 2109 0506
  • Email: tao.jia86(at)outlook.com